2. MAPK/ERK Pathway
  3. MAP4K
  4. HPK1-IN-44

HPK1-IN-44 (Compound 1) 是 HPK1 的抑制剂 (IC50 0.1 nM(40 μM ATP))。

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HPK1-IN-44 Chemical Structure

HPK1-IN-44 Chemical Structure

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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HPK1-IN-44 相关抗体

Top Publications Citing Use of Products

查看 MAP4K 亚型特异性产品:

查看所有亚型
MAP4K2/GCK MAP4K3/GLK MAP4K4/HGK MAP4K5/KHS1 MAP4K6/MINK1 MAP4K7/TNIK MAP4K1/HPK1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HPK1-IN-44 (Compound 1) is an inhibitor of HPK1 (IC50=0.1 nM (40 μM ATP))[1].

IC50 & Target[1]

HPK1

0.1 nM (IC50)

体外研究
(In Vitro)

HPK1-IN-44 的细胞学活性结果分别为 IC50=120.88 nM (pSLP76); EC50=3.67 nM (IL-2 release)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

HPK1-IN-44 相关抗体:
分子量

512.00

Formula

C29H26ClN5O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HPK1-IN-44 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HPK1-IN-44MAP4KMAPK Kinase Kinase KinaseImmune modulationAnti-tumoEnzyme inhibitionInhibitorinhibitorinhibit

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产品名称：
HPK1-IN-44
目录号：
HY-163495
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