Insulin β Chain Peptide (15-23) 

Insulin β Chain Peptide (15-23) is one of the earliest antigenic epitopes to which CD8 T-cells respond^[1][2][3].

从 5 至 8 周龄的 G9Cα^−/− NOD 小鼠中纯化的 CD8 T 细胞可响应 Insulin β Chain Peptide (15-23) (1 µg/mL，24 小时)^[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

胰岛素 β 链肽 (15-23) (50 μg，腹腔注射) 与 CpG 1826 寡核苷酸一起促进 G9Cα^−/−.NOD 小鼠糖尿病的快速发展^[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

1009.18

C₄₄H₇₂N₁₂O₁₃S

247044-67-3

固体

White to off-white

Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly

LYLVCGERG

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

• [1]. Amrani A, et al. Progression of autoimmune diabetes driven by avidity maturation of a T-cell population. Nature. 2000;406(6797):739-742.  [Content Brief]

  [2]. Takaki T, et al. Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4. J Immunol. 2004;173(4):2530-2541.  [Content Brief]

  [3]. Wong FS, et al. Activation of insulin-reactive CD8 T-cells for development of autoimmune diabetes. Diabetes. 2009 May;58(5):1156-64.  [Content Brief]