1. Epigenetics Protein Tyrosine Kinase/RTK JAK/STAT Signaling Stem Cell/Wnt
  2. JAK
  3. JAK-IN-30

JAK-IN-30 (化合物 31) 是一种具有水溶性的 JAK 抑制剂,其对 JAK2JAK1JAK3 以及 TYK2IC50 值分别为 2, 15, 18 以及 2 nM。JAK-IN-30 具有研究干眼症 (DED) 的潜力。

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JAK-IN-30 Chemical Structure

JAK-IN-30 Chemical Structure

CAS No. : 2891469-99-9

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规格 价格 是否有货
1 mg ¥1300
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5 mg ¥4950
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查看 JAK 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

JAK-IN-30 (compound 31) is a water-soluble JAK inhibitor with IC50 values of 2, 15, 18 and 2 nM for JAK2, JAK1, JAK3 and TYK2, respectively. JAK-IN-30 has research potential for dry eye disease (DED)[1].

IC50 & Target[1]

JAK1

15 nM (IC50)

JAK2

2 nM (IC50)

JAK3

18 nM (IC50)

Tyk2

2 nM (IC50)

分子量

398.53

Formula

C19H26N8S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
JAK-IN-30
目录号:
HY-154994
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