1. 多肽产品
  2. 多肽及其衍生物
  3. JMV 236

JMV 236是一种胆囊收缩素拮抗剂,具有抑制食欲的活性。JMV 236通过肠道内源性肽PrRP和CCK1受体的相互作用,影响食物摄入的调节。JMV 236的使用能激活位于NTS的PrRP神经元,从而加强其抑制食欲的效果。JMV 236对与食物摄入相关的中枢神经系统区域有显著影响,尤其是在饥饿状态下。

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Custom Peptide Synthesis

JMV 236 Chemical Structure

JMV 236 Chemical Structure

CAS No. : 113137-57-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

JMV 236 is a cholecystokinin antagonist with appetite-suppressing activity. JMV 236 affects the regulation of food intake through the interaction of the intestinal endogenous peptide PrRP and the CCK1 receptor. The administration of JMV 236 activates PrRP neurons located in the NTS, thereby enhancing its appetite-suppressing effect. JMV 236 has significant effects on areas of the central nervous system associated with food intake, especially during states of starvation[1].

分子量

1207.31

Formula

C56H74N10O18S

CAS 号
Sequence

{Boc-Tyr(SO3)}-Nle-Gly-Trp-Nle-Asp-Phe-NH2

Sequence Shortening

{Boc-Tyr(SO3)}-{Nle}-GW-{Nle}-DF-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
JMV 236
目录号:
HY-P2025
需求量: