2. Neuronal Signaling
  3. Amyloid-β
  4. Kayaflavone

Kayafavone 是一种氨基黄酮型双类黄酮。Kayyavone 对 PC-12 细胞 amyloid-β 细胞毒性有抑制作用，EC50 值为 5.29 μM。Kayaflavone 有望用于阿尔茨海默病研究。

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Kayaflavone Chemical Structure

Kayaflavone Chemical Structure

CAS No. : 481-45-8

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规格 价格 是否有货 数量
1 mg ￥3220
1 - 2 周
5 mg 现货 1 - 2 周
10 mg   询价  
50 mg   询价  

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Kayaflavone 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kayaflavone is an amentoflavone type biflavonoid. Kayaflavone has an inhibitory activity against amyloid-β42 cytotoxicity in PC-12 cells with an EC50 value of 5.29 μΜ. Kayaflavone is promising for research of Alzheimer’s disease[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
PC-12 EC50
5.29 μM
Compound: 15
Neuroprotective activity against 0.1 uM amyloid beta 42-induced toxicity in rat PC12 cells assessed as cell viability after 24 hrs by MTT assay
Neuroprotective activity against 0.1 uM amyloid beta 42-induced toxicity in rat PC12 cells assessed as cell viability after 24 hrs by MTT assay
[PMID: 26004578]
分子量

580.54

Formula

C33H24O10
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Kayaflavone 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kayaflavone481-45-8Amyloid-ββ-amyloid peptideAβAbetabiflavonoidamyloid-β42PC-12 cellsAlzheimer’s diseaseInhibitorinhibitorinhibit

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