2. PROTAC
  3. Ligands for E3 Ligase
  4. Lenalidomide-4-aminomethyl

Lenalidomide-4-aminomethyl 是一种基于 Lenalidomide 的 E3 泛素连接酶 cereblon (CRBN) 配体，用于募集 cereblon 蛋白。Lenalidomide-4-aminomethyl 可通过 linker 连接到蛋白质配体上形成 PROTAC。

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Lenalidomide-4-aminomethyl Chemical Structure

Lenalidomide-4-aminomethyl Chemical Structure

CAS No. : 790652-68-5

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Other Forms of Lenalidomide-4-aminomethyl:

Lenalidomide-4-aminomethyl 相关抗体

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查看 Ligands for E3 Ligase 亚型特异性产品:

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lenalidomide-4-aminomethyl is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl can be connected to the ligand for protein by a linker to form PROTAC[1].

IC50 & Target

Cereblon

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Lenalidomide-4-aminomethyl 相关抗体:
分子量

273.29

Formula

C14H15N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Lenalidomide-4-aminomethyl 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lenalidomide-4-aminomethyl790652-68-5Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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