2. PROTAC
  3. Ligands for E3 Ligase
  4. Lenalidomide-4-aminomethyl hydrochloride

Lenalidomide-4-aminomethyl hydrochloride 

目录号: HY-138882A
产品使用指南

摩尔计算器

Lenalidomide-4-aminomethyl hydrochloride 是一种基于 Lenalidomide 的 E3 泛素连接酶 cereblon (CRBN) 配体，用于募集 cereblon 蛋白。Lenalidomide-4-aminomethyl hydrochloride 可通过 linker 连接到蛋白质配体上形成 PROTAC。

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Lenalidomide-4-aminomethyl hydrochloride Chemical Structure

Lenalidomide-4-aminomethyl hydrochloride Chemical Structure

CAS No. : 444289-05-8

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规格 价格 是否有货 数量
5 mg ￥240
3 - 4 周
10 mg ￥400
3 - 4 周
25 mg ￥760
3 - 4 周
50 mg ￥1200
3 - 4 周
100 mg ￥1920
3 - 4 周
200 mg   询价  
500 mg   询价  

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Customer Review

Other Forms of Lenalidomide-4-aminomethyl hydrochloride:

Lenalidomide-4-aminomethyl hydrochloride 相关抗体

Top Publications Citing Use of Products

查看 Ligands for E3 Ligase 亚型特异性产品:

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lenalidomide-4-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1]

IC50 & Target

Cereblon

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Lenalidomide-4-aminomethyl hydrochloride 相关抗体:
分子量

309.75

Formula

C14H16ClN3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Lenalidomide-4-aminomethyl hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lenalidomide-4-aminomethyl444289-05-8Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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目录号：
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