1. Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  2. Thyroid Hormone Receptor Endogenous Metabolite
  3. Liothyronine sodium hydrate

Liothyronine sodium hydrate  (Synonyms: 三碘代甲状腺素钠盐水合物; Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate)

目录号: HY-A0070B 纯度: 98.24%
Data Sheet SDS COA 产品使用指南

Liothyronine sodium hydrate 是一种有效的甲状腺激素。Liothyronine sodium hydrate 是有效的 TRαTRβ 激动剂,对 hTRα 和 hTRβ 的 Ki 值均为 2.33 nM。

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Liothyronine sodium hydrate Chemical Structure

Liothyronine sodium hydrate Chemical Structure

CAS No. : 345957-19-9

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Other Forms of Liothyronine sodium hydrate:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Liothyronine (T3, 100 nM) sodium hydrate stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. Liothyronine sodium hydrate binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium hydrate promotes growth, induces differentiation and regualtes metabolic effects[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
NCT NumberSponsorConditionStart DatePhase
NCT04354688ZimVie
Edentulous Jaw
October 19, 2019Not Applicable
NCT01153360Yonsei University
Non-thyroidal Illness Syndrome
June 2010Not Applicable
NCT00531713Copenhagen University Hospital at Herlev
Quality of Life|Depression
April 2003Phase 4
Formula

C15H12I3NO4.xH2O.Na

CAS 号
性状

固体

颜色

White to light brown

中文名称

三碘代甲状腺素钠盐水合物

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

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产品名称:
Liothyronine sodium hydrate
目录号:
HY-A0070B
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