2. Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. Thyroid Hormone Receptor Endogenous Metabolite
  4. Liothyronine sodium hydrate

Liothyronine sodium hydrate  (Synonyms: 三碘代甲状腺素钠盐水合物; Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate)

目录号: HY-A0070B
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摩尔计算器

Liothyronine sodium hydrate 是一种有效的甲状腺激素。Liothyronine sodium hydrate 是有效的 TRα 和 TRβ 激动剂，对 hTRα 和 hTRβ 的 Ki 值均为 2.33 nM。

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Liothyronine sodium hydrate Chemical Structure

Liothyronine sodium hydrate Chemical Structure

CAS No. : 345957-19-9

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Liothyronine sodium hydrate 的其他形式现货产品:

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Liothyronine sodium hydrate 相关抗体

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  • 生物活性

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生物活性

Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Liothyronine (T3, 100 nM) sodium hydrate stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. Liothyronine sodium hydrate binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium hydrate promotes growth, induces differentiation and regualtes metabolic effects[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Liothyronine sodium hydrate 相关抗体:
Clinical Trial
Formula

C15H12I3NO4.xH2O.Na
CAS 号
中文名称

三碘代甲状腺素钠盐水合物
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Liothyronine sodium hydrate 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Liothyronine sodium345957-19-9Triiodothyronine sodium3,3',5-Triiodo-L-thyronine sodiumT3 sodium三碘代甲状腺素钠盐水合物Thyroid Hormone ReceptorEndogenous MetaboliteTHRthyroid hormoneTRαTRβInhibitorinhibitorinhibit

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