2. Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. Thyroid Hormone Receptor Endogenous Metabolite
  4. Liothyronine hydrochloride

Liothyronine hydrochloride  (Synonyms: 三碘代甲状腺素盐酸盐; Triiodothyronine hydrochloride; 3,3',5-Triiodo-L-thyronine hydrochloride; T3 hydrochloride)

目录号: HY-A0070C
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摩尔计算器

Liothyronine hydrochloride 是一种有效的甲状腺激素。Liothyronine hydrochloride 是有效的 TRα 和 TRβ 激动剂，对 hTRα 和 hTRβ 的 Ki 值均为 2.33 nM。

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Liothyronine hydrochloride Chemical Structure

Liothyronine hydrochloride Chemical Structure

CAS No. : 6138-47-2

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Liothyronine hydrochloride 的其他形式现货产品:

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Other Forms of Liothyronine hydrochloride:

Liothyronine hydrochloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Liothyronine hydrochloride is an active form of thyroid hormone. Liothyronine hydrochloride is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3].

IC50 & Target

TRβ1[1][2]
体外研究
(In Vitro)

Liothyronine (T3, 100 nM) hydrochloride stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. Liothyronine hydrochloride binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine hydrochloride promotes growth, induces differentiation and regualtes metabolic effects[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Liothyronine hydrochloride 相关抗体:
Clinical Trial
分子量

687.43

Formula

C15H13ClI3NO4
CAS 号
中文名称

三碘代甲状腺素盐酸盐
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Liothyronine hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Liothyronine6138-47-2Triiodothyronine3,3',5-Triiodo-L-thyronineT3三碘代甲状腺素盐酸盐T 3T-3Thyroid Hormone ReceptorEndogenous MetaboliteTHRthyroid hormoneTRαTRβInhibitorinhibitorinhibit

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