2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. NO Synthase Reactive Oxygen Species
  4. Luteolin 5-O-glucoside

Luteolin 5-O-glucoside  (Synonyms: 木犀草素-5-O-葡萄糖苷)

目录号: HY-N2008 纯度: 97.18%
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摩尔计算器

Luteolin 5-O-glucoside 来自 Cirsium maackii，具有抗炎活性。Luteolin 5-O-glucoside 抑制 LPS 诱导的 NO 生成和 t-BHP 诱导的 ROS 生成。Luteolin 5-O-glucoside 作用于巨噬细胞，还抑制 iNOS 和 COX-2 表达。

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Luteolin 5-O-glucoside Chemical Structure

Luteolin 5-O-glucoside Chemical Structure

CAS No. : 20344-46-1

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Luteolin 5-O-glucoside 相关抗体

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nNOS iNOS eNOS

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Luteolin 5-O-glucoside, a major flavonoidfrom Cirsium maackii, possesses anti-inflammatory activity. Luteolin 5-O-glucoside inhibits LPS-induced NO production and t-BHP-induced ROS generation. Luteolin 5-O-glucoside suppresses the expression of iNOS and COX-2 in macrophages[1].

IC50 & Target

iNOS

 

体外研究
(In Vitro)

Luteolin 5-O-glucoside, at a non-toxic concentration, inhibits LPS-induced NO production and t-BHP-induced ROS generation in a dose-dependent manner in RAW 264.7 cells. Luteolin 5-O-glucoside also suppresses the expression of iNOS and COX-2 in LPS-stimulated macrophages[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Luteolin 5-O-glucoside 相关抗体:
分子量

448.38

Formula

C21H20O11
CAS 号
性状

固体

颜色

Light yellow to yellow

中文名称

木犀草素-5-O-葡萄糖苷
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥98.0%

COA (266 KB) HNMR (567 KB)

产品使用指南 (1538 KB)
参考文献

Luteolin 5-O-glucoside 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Luteolin 5-O-glucoside20344-46-1木犀草素-5-O-葡萄糖苷NO SynthaseReactive Oxygen SpeciesNitric oxide synthasesNOSReactiveoxygenspeciesROSNitricoxideNOanti-inflammatoryInhibitorinhibitorinhibit

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