2. Apoptosis
  3. Apoptosis
  4. Malvidin chloride

Malvidin chloride  (Synonyms: Syringidin)

目录号: HY-122496 纯度: 98.48%
COA 产品使用指南 技术支持

Malvidin (chloride) 是一种从葡萄中分离出来的生物活性化合物。 Malvidin 通过阻止细胞周期的 G2/M 期和诱导细胞凋亡显示出细胞毒性。Malvidin可用于癌症研究。

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Malvidin chloride Chemical Structure

Malvidin chloride Chemical Structure

CAS No. : 643-84-5

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规格 价格 是否有货 数量
1 mg ￥1250
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5 mg ￥3200
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10 mg ￥5500
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Customer Review

Other Forms of Malvidin chloride:

Malvidin chloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Malvidin (chloride) is a bioactive compound isolated from grape. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
RAW264.7 IC50
9 μM
Compound: Malvidin
Inhibition of ROS production in LPS-induced mouse RAW264.7 cells incubated for 22 hrs by H2DCF-DA staining based analysis
Inhibition of ROS production in LPS-induced mouse RAW264.7 cells incubated for 22 hrs by H2DCF-DA staining based analysis
[PMID: 35932905]
RAW264.7 IC50
9 μM
Compound: Malvidin
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells after 22 hrs by C-400 fluorescent dye-based assay
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells after 22 hrs by C-400 fluorescent dye-based assay
[PMID: 28159411]
RAW264.7 IC50
9 μM
Compound: Malvidin
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells preincubated for 1 hr followed by LPS stimulation after 24 hrs by CMH2DCFDA probe-based fluorescence assay
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells preincubated for 1 hr followed by LPS stimulation after 24 hrs by CMH2DCFDA probe-based fluorescence assay
[PMID: 28384544]
体外研究
(In Vitro)

Malvidin (0~80 μg/mL; 96 hours; U937 cells) shows cytotoxic activity in a dose-dependent pattern[1].
The IC50 value of Malvidin for U937 cells is 40 μg/mL. Malvidin (U937 cells) shows arrest at the G2/M phase of the cell cycle and increases sub G1 hypo-diploid population[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Malvidin chloride 相关抗体:

Cell Viability Assay[1]

Cell Line: U937 cells
Concentration: 0~80 μg/mL
Incubation Time: 96 hours
Result: Showed cytotoxic activity in a dose-dependent pattern.
分子量

366.75

Formula

C17H15ClO7
CAS 号
性状

固体

颜色

Brown to dark brown

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : 16 mg/mL (43.63 mM; 超声加热助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.7267 mL 13.6333 mL 27.2665 mL
5 mM 0.5453 mL 2.7267 mL 5.4533 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 98.48%

COA (173 KB) HNMR (209 KB) LCMS (135 KB)

产品使用指南 (1538 KB)
参考文献

Malvidin chloride 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7267 mL 13.6333 mL 27.2665 mL 68.1663 mL
5 mM 0.5453 mL 2.7267 mL 5.4533 mL 13.6333 mL
10 mM 0.2727 mL 1.3633 mL 2.7267 mL 6.8166 mL
15 mM 0.1818 mL 0.9089 mL 1.8178 mL 4.5444 mL
20 mM 0.1363 mL 0.6817 mL 1.3633 mL 3.4083 mL
25 mM 0.1091 mL 0.5453 mL 1.0907 mL 2.7267 mL
30 mM 0.0909 mL 0.4544 mL 0.9089 mL 2.2722 mL
40 mM 0.0682 mL 0.3408 mL 0.6817 mL 1.7042 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Malvidin643-84-5SyringidinApoptosisbioactiveoryzacytotoxicityarrestapoptosiscancerG2/MInhibitorinhibitorinhibit

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