2. MAPK/ERK Pathway
  3. MAP4K JNK
  4. MAP4K4-IN-6

MAP4K4-IN-6 (Compound 15f) 是一种 MAP4K4 抑制剂 (IC50: 80 nM)。MAP4K4-IN-6 可降低 c-Jun 磷酸化。MAP4K4-IN-6 具有神经保护作用。MAP4K4-IN-6 可提高运动神经元的活力。MAP4K4-IN-6 可用于肌萎缩侧索硬化症 (ALS) 的研究。

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MAP4K4-IN-6 Chemical Structure

MAP4K4-IN-6 Chemical Structure

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MAP4K4-IN-6 相关抗体

Top Publications Citing Use of Products

查看 MAP4K 亚型特异性产品:

查看所有亚型
MAP4K2/GCK MAP4K3/GLK MAP4K4/HGK MAP4K5/KHS1 MAP4K6/MINK1 MAP4K7/TNIK MAP4K1/HPK1

查看 JNK 亚型特异性产品:

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JNK1 JNK2 JNK3 JNK

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MAP4K4-IN-6 (Compound 15f) is a MAP4K4 inhibitor (IC50: 80 nM). MAP4K4-IN-6 reduces the c-Jun phosphorylation. MAP4K4-IN-6 has neuroprotective effects. MAP4K4-IN-6 increases the viability of motor neurons. MAP4K4-IN-6 can be used for research of Amyotrophic lateral sclerosis (ALS)[1].

分子量

343.32

Formula

C14H12F3N3O2S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MAP4K4-IN-6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MAP4K4-IN-6MAP4KJNKMAPK Kinase Kinase Kinasec-Jun N-terminal kinaseInhibitorinhibitorinhibit

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目录号：
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