2. Protein Tyrosine Kinase/RTK
  3. c-Fms
  4. Mavrilimumab

Mavrilimumab  (Synonyms: 玛弗利木单抗; CAM 3001)

目录号: HY-P99031 纯度: 98.37%
COA

摩尔计算器

Mavrilimumab (CAM 3001) 是一种单克隆抗体，可与粒细胞-巨噬细胞集落刺激因子 (GM-CSF) 受体的 α 亚基结合，并阻断 GM-CSF 下游细胞内信号传导。GM-CSF 可能是与呼吸衰竭和死亡相关的过度活跃炎症反应的介质。

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CAS No. : 1085337-57-0

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规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥7500
In-stock
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50 mg   询价  

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Mavrilimumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death[1].

同型

Human IgG4 lambda
推荐同型对照抗体
种属

Human
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

玛弗利木单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 lambda2
Biological Activity
  • Loaded Mavrilimumab on AHC2 biosensor, can bind GM-CSF R alpha Protein, Human (HEK293, His, HY-P7783) with an affinity constant of 7.867E-10 M as determined in BLI assay.
纯度 & 产品资料
参考文献

Mavrilimumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mavrilimumab1085337-57-0CAM 3001玛弗利木单抗CAM3001CAM-3001c-FmsCSF-1 receptorcolony stimulating factor 1 receptorCSF-1RCSF1Rmonoclonal antibodygranulocyte-macrophage colony stimulating factorGM-CSFhyperactive inflammatory responserespiratory failureInhibitorinhibitorinhibit

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