2. Academic Validation
  3. Epoxomicin, a new antitumor agent of microbial origin

Epoxomicin, a new antitumor agent of microbial origin

  • J Antibiot (Tokyo). 1992 Nov;45(11):1746-52. doi: 10.7164/antibiotics.45.1746.
M Hanada 1,  K Sugawara,  K Kaneta,  S Toda,  Y Nishiyama,  K Tomita,  H Yamamoto,  M Konishi,  T Oki
Affiliations

Affiliation

  • 1 Bristol-Myers Squibb Research Institute, Tokyo, Japan.
PMID: 1468981 DOI: 10.7164/antibiotics.45.1746
Abstract

An actinomycete strain No. Q996-17 produced a novel compound, epoxomicin, which exhibited in vivo antitumor activity against B16 melanoma. Structural studies indicated that it is a new member of the epoxy-beta-aminoketone group, and is closely related to eponemycin.

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