Design, Synthesis, and Bioevaluation of Novel NLRP3 Inhibitor with IBD Immunotherapy from the Virtual Screen

Affiliations

• 1 School of Pharmacy & Minhang Hospitol, Fudan University, Shanghai 201301, China.
• 2 Department of Biopharmaceuticals, School of Pharmacy, Fudan University, Shanghai 201301, China.
• 3 Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201301, China.
• 4 Key Laboratory for Advanced Materials and Feringa Nobel Prize Scientist Joint Research Center, Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, Frontiers Science Center for Materiobiology and Dynamic Chemistry, East China University of Science and Technology, Shanghai 200237, China.