Autoantibodies to BACE1 promote Aβ accumulation and neurodegeneration in Alzheimer's disease

Affiliations

• 1 Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Third Military Medical University, Chongqing, China.
• 2 Key Laboratory of Aging and Brain Disease, Chongqing, China.
• 3 Centre of Health Management, Daping Hospital, Third Military Medical University, Chongqing, China.
• 4 The Florey Institute, The University of Melbourne, Parkville, VIC, Australia.
• 5 The Australian E-Health Research Centre, CSIRO, Herston, QLD, Australia.
• 6 CogState, Melbourne, VIC, Australia.
• 7 School of Medical Sciences, Sarich Neuroscience Research Institute, Edith Cowan University, Nedlands, WA, Australia.
• 8 Department of Biomedical Sciences, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW, Australia.
• 9 Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Australia.
• 10 The Florey Institute, The University of Melbourne, Parkville, VIC, Australia. c.masters@unimelb.edu.au.
• 11 Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Third Military Medical University, Chongqing, China. yanjiang_wang@tmmu.edu.cn.
• 12 Key Laboratory of Aging and Brain Disease, Chongqing, China. yanjiang_wang@tmmu.edu.cn.
• 13 Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China. yanjiang_wang@tmmu.edu.cn.
• 14 Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Third Military Medical University, Chongqing, China. yuhuiliu@tmmu.edu.cn.
• 15 Key Laboratory of Aging and Brain Disease, Chongqing, China. yuhuiliu@tmmu.edu.cn.
• # Contributed equally.