2. Academic Validation
  3. Antarelix (EP 24332) a novel water soluble LHRH antagonist

Antarelix (EP 24332) a novel water soluble LHRH antagonist

  • Biomed Pharmacother. 1993;47(2-3):107-10. doi: 10.1016/0753-3322(93)90299-z.
R Deghenghi 1,  F Boutignon,  P Wüthrich,  V Lenaerts
Affiliations

Affiliation

  • 1 Europeptides, Argenteuil, France.
PMID: 7693007 DOI: 10.1016/0753-3322(93)90299-z
Abstract

A novel water soluble LHRH antagonist (EP 24332-Antarelix) is described. Its activity in vitro and in vivo in several animal models is given. Antarelix (Ac-D-Nal, D-Cpa, D-Pal, Ser, Tyr, D-Hci, Leu, Lys-(iPr), Pro, D-Ala-NH2) in view of its potency, modest histamine-liberating activity and high water solubility has been selected for further development.

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