2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. MCPG sodium

MCPG 是一种羧基苯基甘氨酸。MCPG能阻断代谢型谷氨酸受体 (mGluRs) , 具有mGluR亚型的拮抗活性。MCPG 可用作研究长时程增强（LTP）的诱导和维持。

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MCPG sodium Chemical Structure

MCPG sodium Chemical Structure

CAS No. : 1303994-09-3

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MCPG sodium 相关抗体

Top Publications Citing Use of Products

查看 mGluR 亚型特异性产品:

查看所有亚型
mGluR1 mGluR2 mGluR3 mGluR4 mGluR5 mGluR6 mGluR7 mGluR8 mGluR

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MCPG is a carboxylic phenyl glycine. MCPG can block metabotropic glutamate receptor (mGluR)(HY-15129) and has antagonistic activity of mGluR subtype. MCPG can be used to study the induction and maintenance of long-term potentiation (LTP) [1].

体外研究
(In Vitro)

MCPG (300 μM, 1, 和 3 mM) 在海马体切片中对1S、3R-ACPD诱导磷酸肌醇 (PPI) 水解的浓度依赖性增加有抑制作用[1]。
MCPG (20 mM, 200 mM) 对长时程增强 (LTP) 有选择性阻断作用 (20 mM) ，也能抑制破伤风诱导的短时程增强 (STP) (200 mM) [1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

MCPG sodium 相关抗体:
体内研究
(In Vivo)

MCPG (脑室注射) 在雄性维斯塔大鼠中可消除强直刺激带来的齿状回场兴奋性突触后电位 (fEPSP) 的增强作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

231.18

Formula

C10H10NNaO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MCPG sodium 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MCPG1303994-09-3mGluRMetabotropic glutamate receptorshippocampuslong-term potentiation (LTP)metabotropic glutamate receptor (mGluR)dentate gyrusInhibitorinhibitorinhibit

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目录号：
HY-103570
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