2. Anti-infection Immunology/Inflammation GPCR/G Protein Neuronal Signaling
  3. Penicillin-binding protein (PBP) Bacterial Antibiotic Histamine Receptor
  4. Methicillin sodium hydrate

Methcillin sodium hydrate 是一种窄谱 β-内酰胺类抗生素，通过抑制青霉素结合蛋白 (penicillin-binding proteins, PBP) 发挥作用。Methcillin sodium hydrate 对青霉素耐药性的金黄色葡萄球菌 Staphylococcus aureu 和表皮葡萄球菌 Staphylococcus epidermidis 有活性。Methcillin sodium hydrate 可用于研究皮肤感染、骨髓炎和心内膜炎等疾病。

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Methicillin sodium hydrate Chemical Structure

Methicillin sodium hydrate Chemical Structure

CAS No. : 7246-14-2

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Methicillin sodium hydrate 的其他形式现货产品:

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Other Forms of Methicillin sodium hydrate:

Methicillin sodium hydrate 相关抗体

Top Publications Citing Use of Products

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

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H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis[1].

IC50 & Target

β-lactam

 

体外研究
(In Vitro)

Methcillin sodium hydrate (20 μg/mL, 24 h) results in a rapid decrease in CFU of S. aureus[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Methicillin sodium hydrate 相关抗体:
体内研究
(In Vivo)

Methicillin sodium hydrate (Intramuscular administration, 40 mg/kg every 6 h, 5 days), in S. aureus.-infected rabbits[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

420.41

Formula

C17H21N2NaO7S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Methicillin sodium hydrate 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methicillin sodium7246-14-2Penicillin-binding protein (PBP)BacterialAntibioticHistamine Receptorβ-lactam antibioticpenicillin-binding proteinskin infectionsStaphylococcus epidermidisMRSA.Inhibitorinhibitorinhibit

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