2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Methoxamine

Methoxamine 是一种选择性 alpha1 肾上腺素能受体激动剂。Methoxamine 引起血管收缩和外周血管阻力增加。Methoxamine通过 Prazosin 敏感机制在兔肺动脉显著增加 ATP、ADP 和 AMP 的溢出，但不增加腺苷的溢出。

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Methoxamine Chemical Structure

Methoxamine Chemical Structure

CAS No. : 390-28-3

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Methoxamine 的其他形式现货产品:

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Methoxamine 相关抗体

Top Publications Citing Use of Products

查看 Adrenergic Receptor 亚型特异性产品:

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α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Methoxamine is a selective alpha1-adrenergic receptor agonist. Methoxamine causes vasoconstriction and increased peripheral vascular resistance[1][2]. Methoxamine hydrochloride significantly increased the overflow of ATP, ADP and AMP, but not adenosine, by a prazosin-sensitive mechanism in the rabbit pulmonary artery[3].

体内研究
(In Vivo)

Methoxamine (0.025 mg/kg; femoral vein) has a greater effect on peripheral resistance vessels than on Winkessel vessels in the rat systemic circulation[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar-Kyoto rats weighing 320-47 g ( based on the exponentially tapered T-tube model)[2]
Dosage: 0.025 mg/kg
Administration: Femoral vein
Result: Had a greater effect on the peripheral resistance vessels than on the Winkessel vessels in the rat systemic circulation.
分子量

211.26

Formula

C11H17NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Methoxamine 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Methoxamine390-28-3Adrenergic ReceptorBeta ReceptorvasoconstrictionperipheralvascularhypertensiveInhibitorinhibitorinhibit

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