2. PROTAC Protein Tyrosine Kinase/RTK
  3. PROTACs Bcr-Abl
  4. ML 2-23

ML 2-23 是一种有效的 PROTAC BCR-ABL 降解剂。 ML 2-23 在白血病细胞中以蛋白酶体依赖性方式选择性降解 BCR-ABL。

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ML 2-23 Chemical Structure

ML 2-23 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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ML 2-23 相关抗体

Top Publications Citing Use of Products

查看 PROTACs 亚型特异性产品:

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ML 2-23 is a potent PROTAC BCR-ABL degrader. ML 2-23 is selectively degrade BCR-ABL in a proteasome-dependent manner in leukemia cells[1].

体外研究
(In Vitro)

ML 2-23 (1 μM; 12 h; K562 细胞) 以蛋白酶体依赖性方式降解 BCR-ABL[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

ML 2-23 相关抗体:

Western Blot Analysis[1]

Cell Line: K562 cells
Concentration: 1 μM
Incubation Time: 12 h
Result: Degraded BCR-ABL in K562 cells.
分子量

1052.86

Formula

C47H53BrCl2N10O7S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ML 2-23 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ML 2-23PROTACsBcr-Ablleukemia cellsproteasomeInhibitorinhibitorinhibit

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产品名称：
ML 2-23
目录号：
HY-153582
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