1. Metabolic Enzyme/Protease
  2. Lipoxygenase
  3. MLS000536924

MLS000536924是一种强效且选择性的人上皮15-脂氧合酶-2抑制剂,具有竞争性活性。MLS000536924在抑制h15-LOX-2方面表现出超过50倍的选择性,能够有效地应用于研究其在动脉粥样硬化、囊性纤维化和铁死亡中的作用。MLS000536924的结合模式与其他抑制剂相比,显示出更强的对蛋白质运动的限制性,进一步验证其较高的生物活性。

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MLS000536924 Chemical Structure

MLS000536924 Chemical Structure

CAS No. : 511306-37-9

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查看 Lipoxygenase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MLS000536924 is a potent and selective inhibitor of human epithelial 15-lipoxygenase-2 with competitive activity. MLS000536924 exhibits more than 50-fold selectivity in inhibiting h15-LOX-2 and can be effectively applied to study its role in atherosclerosis, cystic fibrosis, and ferroptosis. The binding mode of MLS000536924 shows stronger restriction of protein movement than other inhibitors, further verifying its higher biological activity[1].

分子量

281.38

Formula

C16H15N3S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MLS000536924
目录号:
HY-116919
需求量: