2. GPCR/G Protein
  3. Platelet-activating Factor Receptor (PAFR)
  4. Modipafant

Modipafant  (Synonyms: UK-80067)

目录号: HY-108908A
产品使用指南

摩尔计算器

Modipafant (UK-80067)，UK-74505 的对映体，是一种高效、具有口服活性的选择性的血小板活化因子 (PAF) 拮抗剂。Modipafant 展示了大约两倍于 UK-74505 的内在效力。

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Modipafant Chemical Structure

Modipafant Chemical Structure

CAS No. : 122957-06-6

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规格 是否有货
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Other Forms of Modipafant:

Modipafant 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Modipafant (UK-80067), the (+)-enantiomer of UK-74505, is a potent, orally active, and selective platelet-activating factor (PAF) antagonist. Modipafant exhibits approximately double the intrinsic potency of UK-74505[1][2].

体外研究
(In Vitro)

when preincubated with rabbit platelets, the potency of antagonizing PAF induced aggregation increased markedly when preincubation time with Modipafant was increased from 2 min (IC50=5.6 nM) to 60 min (IC50=0.34 nM)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Modipafant 相关抗体:
Clinical Trial
分子量

605.09

Formula

C34H29ClN6O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Modipafant 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Modipafant122957-06-6UK-80067UK80067UK 80067Platelet-activating Factor Receptor (PAFR)enantiomerplatelet-activatingfactorrabbitplateletsInhibitorinhibitorinhibit

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