2. Antibody-drug Conjugate/ADC Related
  3. Radionuclide-Drug Conjugates (RDCs)
  4. NCS-MP-NODA

NCS-MP-NODA  (Synonyms: NODA-Bz-SCN)

目录号: HY-164576
产品使用指南

摩尔计算器

NCS-MP-NODA (NODA-Bz-SCN) 是一种双功能螯合剂，可用于结合对 PD-L1 具有高度特异性的标记肽 DK222。通过氟化铝法合成相应的氟化放射性，NCS-MP-NODA 靶向 DK222 而获得放射性类似物 [18/19F]DK222。[18F]DK222 可以在多种癌症类型的异种移植模型中，通过 PET 示踪，对体内 PD-L1 量化。

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NCS-MP-NODA Chemical Structure

NCS-MP-NODA Chemical Structure

CAS No. : 1374994-81-6

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

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NCS-MP-NODA 相关抗体

Top Publications Citing Use of Products

查看 Radionuclide-Drug Conjugates (RDCs) 亚型特异性产品:

查看所有亚型
RDC Peptide RDC Antibody RDC Bifunctional Chelator RDC Linker Other

  • 生物活性

  • 纯度 & 产品资料

生物活性

NCS-MP-NODA (NODA-Bz-SCN) is a bifunctional chelator that can be used to bind to the labeled peptide DK222 with high specificity for PD-L1. The corresponding fluorinated radioactive is synthesized by the aluminum fluoride method, and NCS-MP-NODA targets DK222 to obtain the radioactive analog [18/19F]DK222. [18F]DK222 can quantify PD-L1 in vivo via PET tracking in xenograft models of multiple cancer types.

IC50 & Target

RDC Bifunctional Chelator

 

分子量

392.47

Formula

C18H24N4O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

NCS-MP-NODA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NCS-MP-NODA1374994-81-6NODA-Bz-SCNRadionuclide-Drug Conjugates (RDCs)Inhibitorinhibitorinhibit

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