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  3. 多肽及其衍生物
  4. 激素肽与神经肽 抑制剂与底物肽
  5. Neuropeptide W-23 (human)

Neuropeptide W-23 (human)  (Synonyms: NPW-23)

目录号: HY-P1035 纯度: 99.84%
COA 产品使用指南

摩尔计算器

Neuropeptide W-23 (human) (NPW-23) 是 Neuropeptide W 的主要活性形式，为 NPBW1 (GPR7) 和 NPBW2 (GPR8) 的内源性激动剂。

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Custom Peptide Synthesis

Neuropeptide W-23 (human) Chemical Structure

Neuropeptide W-23 (human) Chemical Structure

CAS No. : 383415-79-0

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规格 价格 是否有货 数量
1 mg ￥1500
In-stock
5 mg ￥4500
In-stock
10 mg 现货 询价
50 mg   询价  
100 mg   询价  

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Customer Review

Other Forms of Neuropeptide W-23 (human):

Neuropeptide W-23 (human) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Neuropeptide W-23 (human) (NPW-23), the active form of Neuropeptide W, is an endogenous agonist of NPBW1 (GPR7) and NPBW2 (GPR8)[1].

IC50 & Target

NPBW1, NPBW2[1]
体外研究
(In Vitro)

Neuropeptide W-23 (human) (NPW-23) increases the ICa,L in transfected human embryonic kidney 293 cells and VSMCs via GPR7[1].
Neuropeptide W-23 (human) increases the expression of pan phospho-PKC, intracellular diacylglycerol level, and the second messenger catalyzed by PLC[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Neuropeptide W-23 (human) 相关抗体:
体内研究
(In Vivo)

Neuropeptide W-23 (human) (NPW-23) (0.3-3.0 nM; intracerebroventricular injection; 2 μL) increases total behavioral activity, including locomotion and grooming in conscious rats[2].
Neuropeptide W-23 (human) (NPW-23) (2-8 nM; i.c.v.; 10 μL) shows anorexigenic effect in rats[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Harlan Sprague-Dawley rats, 250–300 g[2]
Dosage: 0.3, 1.0 and 3.0 nM
Administration: Intracerebroventricular injection, 2 μL
Result: Caused significant increases in mean arterial pressure. Demonstrated a significant increase in total activity, ambulatory activity, and duration of stereotypy.
Animal Model: Male Wistar rats weighing 250–300 g[3]
Dosage: 2, 4, 6 and 8 nM
Administration: Intra-cerebroventricular injection, 10 μL
Result: Decreased dark feeding and fasting-induced feeding, decreased feeding intake and weight gain.
分子量

2584.01

Formula

C119H183N35O28S
CAS 号
性状

固体

颜色

White to off-white

Sequence

Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu
Sequence Shortening

WYKHVASPRYHTVGRAAGLLMGL
中文名称

神经肽 W-23 (人)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : ≥ 50 mg/mL (19.35 mM; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.3870 mL 1.9350 mL 3.8700 mL
5 mM 0.0774 mL 0.3870 mL 0.7740 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Neuropeptide W-23 (human) 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.3870 mL 1.9350 mL 3.8700 mL 9.6749 mL
5 mM 0.0774 mL 0.3870 mL 0.7740 mL 1.9350 mL
10 mM 0.0387 mL 0.1935 mL 0.3870 mL 0.9675 mL
15 mM 0.0258 mL 0.1290 mL 0.2580 mL 0.6450 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neuropeptide W-23 (human)383415-79-0NPW-23神经肽 W-23 (人)NPW23NPW 23OthersNPBW1NPBW2GPR7GPR8Neuropeptide Whypetensionanorexigenic effectInhibitorinhibitorinhibit

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目录号：
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