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  4. Nevirapine quinone methide

Nevirapine quinone methide是奈韦拉平的活性代谢物，是一种非核苷逆转录酶抑制剂 (NNRTI)，用于抑制 HIV-1 感染和艾滋病。Nevirapine quinone methide因其代谢活化途径而与严重的皮肤和肝脏损伤有关。Nevirapine quinone methide已被证明可抑制 CYP3A4，这可能导致其肝毒性。

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Nevirapine quinone methide Chemical Structure

Nevirapine quinone methide Chemical Structure

CAS No. : 1061160-22-2

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Nevirapine quinone methide 相关抗体

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生物活性

Nevirapine quinone methide is an active metabolite of Nevirapine, serving as a non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV-1 infection and AIDS. Nevirapine quinone methide is associated with severe skin and liver injuries due to its metabolic activation pathways. Nevirapine quinone methide has been shown to inhibit CYP3A4, which could contribute to its hepatic toxicity.

分子量

264.28

Formula

C15H12N4O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Nevirapine quinone methide 相关分类

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Keywords:

Nevirapine quinone methide1061160-22-2OthersInhibitorinhibitorinhibit

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