2. Anti-infection
  3. Antibiotic Bacterial Penicillin-binding protein (PBP)
  4. Norcyclizine

Norcyclizine  (Synonyms: 1-二苯甲基哌嗪; 1-(Diphenylmethyl)piperazine; 1-Benzhydrylpiperazine)

目录号: HY-W013376
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摩尔计算器

Norcyclizine 是一种哌嗪类化合物，可用于合成抑菌剂。1-Benzhydrylpiperazine 衍生物被发现能增强 β-内酰胺类抗生素 (Oxacillin, HY-B0925A) 对耐 Methicillin (HY-121544) 金黄色葡萄球菌 (MRSA) 的抗菌活性，这种增强作用可能通过抑制 PBP2a 的变构位点来实现。同时 1-Benzhydrylpiperazine 也可作为药理支架用于合成抗癌剂。

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Norcyclizine Chemical Structure

Norcyclizine Chemical Structure

CAS No. : 841-77-0

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Other Forms of Norcyclizine:

Norcyclizine 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Norcyclizine is a piperazine compound that can be used for the synthesis of antimicrobial agents. 1-Benzhydrylpiperazine derivatives have been found to enhance the antibacterial activity of β-lactam antibiotics (Oxacillin, HY-B0925A) against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). This enhancement is likely achieved by inhibiting the allosteric site of PBP2a. Additionally, 1-Benzhydrylpiperazine can also serve as a pharmacological scaffold for the synthesis of anticancer agents[1][2].

分子量

252.35

Formula

C17H20N2
CAS 号
性状

固体

中文名称

1-二苯甲基哌嗪
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献

Norcyclizine 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Norcyclizine841-77-01-(Diphenylmethyl)piperazine 1-Benzhydrylpiperazine1-二苯甲基哌嗪AntibioticBacterialPenicillin-binding protein (PBP)Inhibitorinhibitorinhibit

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