2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. Noxiustoxin

Noxiustoxin 是一种来自墨西哥蝎子 Centruroides noxius 毒液中的一种毒素，可阻断电压依赖性钾通道 (potassium channel) (Kv1.3, IC50=360 nM) 和钙激活钾通道 (potassium channel)。Noxiustoxin 在神经炎症疾病中发挥重要的作用。

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Custom Peptide Synthesis

Noxiustoxin Chemical Structure

Noxiustoxin Chemical Structure

CAS No. : 85205-49-8

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Noxiustoxin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Noxiustoxin is a toxin from the venom of the Mexican scorpion Centruroides noxius which block voltage-dependent potassium channel (Kv1.3, IC50 = 360 nM), and calcium-activated potassium channel. Noxiustoxin plays an important role in neuroinflammatory disease[1][2].

分子量

4195.00

Formula

C174H286N52O54S7
CAS 号
Sequence

Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Ser-Lys-Pro-Cys-Lys-Glu-Leu-Tyr-Gly-Ser-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Asn-Asn-NH2 (Disulfide bridge:Cys7-Cys29;Cys13-Cys34;Cys17-Cys36)
Sequence Shortening

TIINVKCTSPKQCSKPCKELYGSSAGAKCMNGKCKCYNN-NH2 (Disulfide bridge:Cys7-Cys29;Cys13-Cys34;Cys17-Cys36)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Noxiustoxin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Noxiustoxin85205-49-8Potassium ChannelKcsAPotassium Channel InhibitorInhibitorinhibitorinhibit

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产品名称：
Noxiustoxin
目录号：
HY-P2710
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