2. PROTAC
  3. Ligands for E3 Ligase
  4. OICR-8268-acrylic acid

OICR-8268-acrylic acid 是一种 E3 泛素连接酶配体。OICR-8268-acrylic acid 可以通过 linker 与靶蛋白配体连接，形成 OICR41114 (HY-169389)。OICR41114 可用于抗癌研究。

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OICR-8268-acrylic acid Chemical Structure

OICR-8268-acrylic acid Chemical Structure

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OICR-8268-acrylic acid 相关抗体

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查看 Ligands for E3 Ligase 亚型特异性产品:

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

OICR-8268-acrylic acid is a ligand for E3 ubiquitin ligase. OICR-8268-acrylic acid can be connected to the ligand for protein by a linker to form OICR41114 (HY-169389). OICR41114 can be used in anti-cancer research[1].

IC50 & Target

VHL

 

分子量

508.30

Formula

C23H17Cl2F2N3O4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

OICR-8268-acrylic acid 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OICR-8268-acrylic acidLigands for E3 LigaseE3 ligase-recruiting MoietyE3 ubiquitin ligaseOICR41114anti-cancerInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-169390
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