Oleanolic acid-d₃  (Synonyms: 齐墩果酸-d₃; Oleanic acid-d₃; Caryophyllin-d₃)

Oleanolic acid-d₃ is the deuterium labeled Oleanolic Acid[1]. Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities[2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

459.72

C₃₀H₄₅D₃O₃

946530-77-4

508-02-1

齐墩果酸-d₃；土当归酸-d₃；石竹素-d₃；丁香油素-d₃

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Zhao X, et al. Oleanolic acid suppresses the proliferation of lung carcinoma cells by miR-122/Cyclin G1/MEF2D axis. Mol Cell Biochem. 2015 Feb;400(1-2):1-7.  [Content Brief]