2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Ortataxel

Ortataxel  (Synonyms: IDN 5109; BAY 59-8862)

目录号: HY-16371
产品使用指南 技术支持

Ortataxel (IDN 5109; BAY 59-8862) 是 Paclitaxel (HY-B0015) 的衍生物。Ortataxel 多种药物敏感和耐药的癌细胞系具有活性。

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Ortataxel Chemical Structure

Ortataxel Chemical Structure

CAS No. : 186348-23-2

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Ortataxel 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ortataxel (IDN 5109; BAY 59-8862) is a derivative of Paclitaxel (HY-B0015). Ortataxel exhibits activity against multiple drug-sensitive and resistant cancer cell lines[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MCF7 IC50
1.6 nM
Compound: 3
Cytotoxic potency in MCF7 human mammary carcinoma cell line after 72 hr exposure by SRB test
Cytotoxic potency in MCF7 human mammary carcinoma cell line after 72 hr exposure by SRB test
[PMID: 16183281]
MCF7-DOX IC50
32 nM
Compound: 3
Cytotoxic potency in doxorubicin resistant MCF7 cell line after 72 hr exposure by SRB test
Cytotoxic potency in doxorubicin resistant MCF7 cell line after 72 hr exposure by SRB test
[PMID: 16183281]
分子量

871.92

Formula

C44H57NO17
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ortataxel 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ortataxel186348-23-2IDN 5109 BAY 59-8862IDN5109IDN-5109Microtubule/TubulinInhibitorinhibitorinhibit

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