2. Anti-infection
  3. RSV
  4. Palivizumab

Palivizumab  (Synonyms: 帕利珠单抗; MEDI 493)

目录号: HY-P9944 纯度: 99.43%
COA

摩尔计算器

Palivizumab (MEDI 493) 是一种人源化呼吸道合胞病毒 (RSV) 单克隆抗体。Palivizumab 可以结合 RSV F 蛋白， Kd 值为 1.4 nM。Palivizumab 可以预防棉鼠的呼吸道合胞病毒感染。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

CAS No. : 188039-54-5

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥5200
In-stock
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

Palivizumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Palivizumab (MEDI 493) is a humanized monoclonal antibody against respiratory syncytial virus (RSV). Palivizumab can bind to RSV F protein with a Kd value of 1.4 nM. Palivizumab can prevent respiratory syncytial virus infection in cotton mice[1].
同型

Human IgG1 kappa
推荐同型对照抗体
种属

Humanized
体外研究
(In Vitro)

Palivizumab 具有 RSV 中和活性，与 IgG1 蛋白的 EC50 值为 0.95850 nM[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Palivizumab 相关抗体:
体内研究
(In Vivo)

Palivizumab (0.625-5 mg/kg (肌肉注射) 或 0.312-10 mg/kg (静脉注射); 单剂量) 可以预防棉鼠的呼吸道合胞病毒感染[1]。
Palivizumab (0.05 mg/kg; 单剂量; 鼻内给药) 可以在小鼠中预防 RSV 感染[2]。
Palivizumab (15 mg/kg; 单剂量; 皮下注射) 可以抑制 RSV 诱导的大鼠气道神经源性炎症[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: The cotton rat model of RSV infection[1].
Dosage: 0.625-5 mg/kg (i.m.) or 0.312-10 mg/kg (i.v.)
Administration: Intramuscular injection (i.m.) or intravenous injection (i.v.); single dose
Result: Reduced virus replication and did not cause RSV infection or pathological increase in both initial and secondary attacks.
Animal Model: BALB/c mice[2].
Dosage: 0.05 mg/kg
Administration: Intranasally administered; single dose
Result: Reduced the RSV load.
Animal Model: Capsaicin-induced neurogenic inflammation in the airways of rats[3].
Dosage: 15 mg/kg
Administration: Subcutaneous injection (s.c.); single dose
Result: Reduced neurogenic extravasation and neurogenic inflammation.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

帕利珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
纯度 & 产品资料

纯度: 99.43%

COA (264 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Palivizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Palivizumab188039-54-5MEDI 493帕利珠单抗MEDI493MEDI-493RSVRespiratory syncytial virusantibodyrespiratory tract infectionInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Palivizumab
目录号：
HY-P9944
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z