2. Cell Cycle/DNA Damage Epigenetics
  3. PARP
  4. PARP1-IN-33

PARP1-IN-33 (Example 6) 是一个 PARP1 抑制剂 (IC50: 0.41 nM)。 PARP1-IN-33 具有视网膜细胞保护作用，其 EC50 为 0.02 nM（抑制过氧化氢诱导的人视网膜色素上皮细胞的 MTS 活性）。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

我们将采用定制合成服务的方式为您快速提供所需产品和技术服务

PARP1-IN-33 Chemical Structure

PARP1-IN-33 Chemical Structure

CAS No. : 2640677-68-3

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
5 mg ￥1100
In-stock
10 mg ￥1750
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

PARP1-IN-33 相关抗体

Top Publications Citing Use of Products

查看 PARP 亚型特异性产品:

查看所有亚型
PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP7 PARP10 PARP14 PARP15 PARP12 PARP16

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PARP1-IN-33 (Example 6) is a PARP1 inhibitor (IC50: 0.41 nM). PARP1-IN-33 has retinal cytoprotective effect, with an EC50 of 0.02 nM (inhibition on MTS activity of H2O2 induced human retinal pigment epithelial cell)[1].

IC50 & Target[1]

PARP1

0.41 nM (IC50)

体外研究
(In Vitro)

PARP1-IN-33 对过氧化氢引起的视网膜细胞损伤有很强的保护作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PARP1-IN-33 相关抗体:

Cell Viability Assay[1]

Cell Line: H2O2 induced human retinal pigment epithelial cell line
Concentration: Less than 150 nM
Incubation Time: 6 h
Result: Protected against hydrogen peroxide-induced damage to retinal cells.

Cell Viability Assay

Cell Line: H2O2 induced human retinal pigment epithelial cell line
Concentration: Less than 150 nM
Incubation Time: 6 h
Result: Protected against hydrogen peroxide-induced damage to retinal cells.
分子量

426.91

Formula

C23H24ClFN4O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PARP1-IN-33 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PARP1-IN-332640677-68-3PARPpoly ADP ribose polymeraseCytoprotective effectRetinal pigment epithelial cellCell proliferationMTS activityNADH dehydrogenase.Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
PARP1-IN-33
目录号：
HY-164926
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z