2. 天然产物
  3. 植物 黄酮类
  4. 菊科 唇形科 黄酮
  5. 款冬
  6. Pedaliin 6''-acetate

Pedaliin 6''-acetate (compound 10) 是一种可从甘青青兰中分离出的天然产物。Pedaliin 6''-acetate 显示出抗氧化活性并对阿霉素 (DOX) 诱导的 H9c2 心肌细胞毒性具有细胞保护作用，EC50 值为 19.1 μM。

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Pedaliin 6''-acetate Chemical Structure

Pedaliin 6''-acetate Chemical Structure

CAS No. : 160789-41-3

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Pedaliin 6''-acetate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pedaliin 6''-acetate (compound 10) is a natural product that can be isolated from Dracocephalum tanguticum. Pedaliin 6''-acetate shows antioxidative activity and cytoprotective effect on doxorubicin (DOX)-induced toxicity in H9c2 cardiomyocytes with an EC50 value of 19.1 μM[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
H9c2 EC50
19.1 μM
Compound: 10
Cytoprotective activity against doxorubicin-induced cytotoxicity in rat H9c2 cells assessed as cell viability after 24 hrs by MTT assay
Cytoprotective activity against doxorubicin-induced cytotoxicity in rat H9c2 cells assessed as cell viability after 24 hrs by MTT assay
[PMID: 20932762]
体外研究
(In Vitro)

Pedaliin 6''-acetate scavenges 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical with an EC50 value of 95.24 μM[1].
Pedaliin 6''-acetate chelates ferrous ions with an EC50 value of 1.13 mM[1].
Pedaliin 6''-acetate scavenges ABTS+ cation radical with an EC50 value of 76.19 μM[1].
Pedaliin 6''-acetate shows cytoprotective effect on DOX-induced toxicity in H9c2 cardiomyocytes with an EC50 value of 19.1μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Pedaliin 6''-acetate 相关抗体:
分子量

520.44

Formula

C24H24O13
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pedaliin 6''-acetate 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Pedaliin 6''-acetate160789-41-3OthersDracocephalum tanguticumDOXH9c2cardiomyocytescytoprotectiveantioxidativeInhibitorinhibitorinhibit

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