1. GPCR/G Protein Neuronal Signaling NF-κB
  2. mAChR NF-κB
  3. Penehyclidine

Penehyclidine  (Synonyms: 戊乙奎醚)

目录号: HY-142119
产品使用指南

Penehyclidine 是一种抗胆碱能剂,选择性的 M1M3 受体拮抗剂。Penehyclidine 可激活肺组织中的 NF-kβ 并抑制炎症因子的释放。Penehyclidine 可减轻慢性阻塞性肺病 (COPD) 大鼠机械通气时的肺部炎症反应。

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Penehyclidine Chemical Structure

Penehyclidine Chemical Structure

CAS No. : 87827-02-9

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规格 是否有货
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100 mg   询价  
250 mg   询价  

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Penehyclidine 的其他形式现货产品:

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Other Forms of Penehyclidine:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Penehyclidine, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation[1][2].

IC50 & Target

mAChR1

 

mAChR3

 

NF-κB

 

Clinical Trial
分子量

315.45

Formula

C20H29NO2

CAS 号
中文名称

戊乙奎醚

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Penehyclidine
目录号:
HY-142119
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