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Perfluorodecalin  (Synonyms: 全氟萘烷; PP 5; Perfluorodecahydronaphthalene)

目录号: HY-108298 纯度: ≥98.0%
COA 产品使用指南

Perfluorodecalin 液体大量用于玻璃体视网膜手术。在兔子的情况下,填塞超过两天的 Perfluorodecalin 对视网膜有害。全氟萘烷可用于巨大视网膜撕裂的研究。Perfluorodecalin 是一种无毒、不易燃、热稳定、不具备生物累积性的 O2 载体,可用作人造血液。Perfluorodecalin 可增强骨再生和细胞活力。

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Perfluorodecalin Chemical Structure

Perfluorodecalin Chemical Structure

CAS No. : 306-94-5

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears[1][2]. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood[3]. Perfluorodecalin enhances bone regeneration and cell viability[4][5].

体外研究
(In Vitro)

Perfluorodecalin 可延长细胞在厌氧环境中的存活时间,增强骨水泥的放射性不透性、可注射性、内聚力和骨再生活性[4]。 Perfluorodecalin (10% v/v) 可改善封装胰岛移植过程中的缺氧情况并提高细胞活力[5]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[5]

Cell Line: BM cells
Concentration:
Incubation Time: 21 days
Result: Increased number of BM cells.

RT-PCR[5]

Cell Line: islets
Concentration: 10% v/v
Incubation Time:
Result: Decreased HIF-1α expression and increased VEGF expression.
体内研究
(In Vivo)

Perfluorodecalin (1.1-1.5 ml/eye) 会引起白化兔子的视网膜损伤和炎症[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Albino rabbits[2]
Dosage: 1.1-1.5 ml for each eye
Administration: injection into vitreous cavity
Result: Induced appearance of foam cells, preretinal membranes, and the interface necrosis.
分子量

462.08

Formula

C10F18

CAS 号
性状

液体(密度:1.9456 g/cm3

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

溶解性数据
细胞实验: 

DMSO 中的溶解度 : 100 mg/mL (216.41 mM; 超声助溶 (<60°C); 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.1641 mL 10.8206 mL 21.6413 mL
5 mM 0.4328 mL 2.1641 mL 4.3283 mL
查看完整储备液配制表
  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥98.0%

参考文献

Perfluorodecalin 相关分类

完整储备液配制表

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1641 mL 10.8206 mL 21.6413 mL 54.1032 mL
5 mM 0.4328 mL 2.1641 mL 4.3283 mL 10.8206 mL
10 mM 0.2164 mL 1.0821 mL 2.1641 mL 5.4103 mL
15 mM 0.1443 mL 0.7214 mL 1.4428 mL 3.6069 mL
20 mM 0.1082 mL 0.5410 mL 1.0821 mL 2.7052 mL
25 mM 0.0866 mL 0.4328 mL 0.8657 mL 2.1641 mL
30 mM 0.0721 mL 0.3607 mL 0.7214 mL 1.8034 mL
40 mM 0.0541 mL 0.2705 mL 0.5410 mL 1.3526 mL
50 mM 0.0433 mL 0.2164 mL 0.4328 mL 1.0821 mL
60 mM 0.0361 mL 0.1803 mL 0.3607 mL 0.9017 mL
80 mM 0.0271 mL 0.1353 mL 0.2705 mL 0.6763 mL
100 mM 0.0216 mL 0.1082 mL 0.2164 mL 0.5410 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Perfluorodecalin
目录号:
HY-108298
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