2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Apoptosis
  3. PPAR Apoptosis
  4. Perfluorotetradecanoic acid

Perfluorotetradecanoic acid  (Synonyms: 全氟十四酸; PFTeDA)

目录号: HY-W073128
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摩尔计算器

Perfluorotetradecanoic acid (PFTeDA) 是一种 PPARγ 抑制剂。Perfluorotetradecanoic acid 与人 PPARγ 配体结合域结合，IC50 为 22.8 μM，Kd 为 157.8 μM。Perfluorotetradecanoic acid 通过诱导氧化应激和细胞凋亡 (Apoptosis) 来抑制 Leydig 细胞的功能。Perfluorotetradecanoic acid 刺激皮质酮生物合成，但抑制醛固酮生成。

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Perfluorotetradecanoic acid Chemical Structure

Perfluorotetradecanoic acid Chemical Structure

CAS No. : 376-06-7

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Perfluorotetradecanoic acid 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Perfluorotetradecanoic acid (PFTeDA) is a PPARγ inhibitor. Perfluorotetradecanoic acid binds to human PPARγ ligand binding domain with IC50 of 22.8 μM, Kd of 157.8 μM. Perfluorotetradecanoic acid inhibits the function of Leydig cells by inducing oxidative stress and apoptosis. Perfluorotetradecanoic acid stimulates corticosterone biosynthesis but inhibits aldosterone production[1][2][3].

分子量

714.11

Formula

C14HF27O2
CAS 号
中文名称

全氟十四酸
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Perfluorotetradecanoic acid 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Perfluorotetradecanoic acid376-06-7PFTeDA全氟十四酸PPARApoptosisPeroxisome proliferator-activated receptorsInhibitorinhibitorinhibit

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