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  4. PF-05387252

PF-05387252是一种有效且选择性的IRAK4抑制剂，具有抑制内源性TLR信号通路的活性。PF-05387252在实验模型中显示出抗炎活性，可能对抑制银屑病具有潜在的临床应用价值。虽然PF-05387252及其相关化合物在动物模型中已表现出抗炎效果，但其在银屑病抑制中的疗效尚未得到验证。

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PF-05387252 Chemical Structure

PF-05387252 Chemical Structure

CAS No. : 1604034-71-0

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PF-05387252 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PF-05387252 is a potent and selective IRAK4 inhibitor with the activity of inhibiting endogenous TLR signaling pathways. PF-05387252 has shown anti-inflammatory activity in experimental models and may have potential clinical application value in inhibiting psoriasis. Although PF-05387252 and its related compounds have shown anti-inflammatory effects in animal models, their efficacy in inhibiting psoriasis has not yet been verified[1].

分子量

429.51

Formula

C25H27N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PF-05387252 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-053872521604034-71-0PF05387252PF 05387252OthersInhibitorinhibitorinhibit

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