2. PI3K/Akt/mTOR Stem Cell/Wnt
  3. GSK-3
  4. PfGSK3/PfPK6-IN-2

PfGSK3/PfPK6-IN-2 是一种有效的 PfGSK3/PfPK6 (Plasmodium falciparum GSK3/PK6) 双重抑制剂 (IC50 分别为 172 nM 和 11 nM)。PfGSK3/PfPK6-IN-2 可用于疟疾的研究。

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PfGSK3/PfPK6-IN-2 Chemical Structure

PfGSK3/PfPK6-IN-2 Chemical Structure

CAS No. : 2797225-47-7

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PfGSK3/PfPK6-IN-2 相关抗体

Top Publications Citing Use of Products

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GSK-3 GSK-3α GSK-3β

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PfGSK3/PfPK6-IN-2 is a potent dual PfGSK3/PfPK6 (Plasmodium falciparum GSK3/PK6) inhibitor (IC50: 172 nM and 11 nM respectively). PfGSK3/PfPK6-IN-2 can be used in the research of Malaria[1].

IC50 & Target

Plasmodium falciparum GSK3/PK6 (PfGSK3/PfPK6)[1]
体外研究
(In Vitro)

PfGSK3/PfPK6-IN-2 (compound 23d) inhibits P. falciparum 3D7 load in erythrocytes (EC50: 552 nM)[1].
PfGSK3/PfPK6-IN-2 (2 μM) shows cytotoxicity against HepG2 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PfGSK3/PfPK6-IN-2 相关抗体:
分子量

502.46

Formula

C24H25Cl2N5OS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PfGSK3/PfPK6-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PfGSK3/PfPK6-IN-22797225-47-7GSK-3Glycogen synthase kinase-3Glycogen synthase kinase 3ErythrocytesP. falciparumMalariaHepG2Inhibitorinhibitorinhibit

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