1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. Phomopsinamine A

Phomopsinamine A 是 Phomopsin A (HY-N6793) 的衍生物。Phomopsinamine A 是微管蛋白聚合 (tubulin polymerization) 的抑制剂,IC50 为 0.53 μM。Phomopsinamine A 抑制 Vinblastine (HY-13780) 与微管蛋白的结合 (IC50 =0.56 μM),促进 Colchicine (HY-16569) 与微管蛋白的结合 (IC50 =0.32 μM)。

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Phomopsinamine A Chemical Structure

Phomopsinamine A Chemical Structure

CAS No. : 89085-54-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Phomopsinamine A is a derivative of Phomopsin A (HY-N6793). Phomopsinamine A is an inhibitor for tubulin polymerization with IC50 of 0.53 μM. Phomopsinamine A inhibits the binding of Vinblastine (HY-13780) to tubulin (IC50 =0.56 μM), promotes the the binding of Colchicine (HY-16569) to tubulin (IC50 =0.32 μM)[1].

分子量

675.17

Formula

C32H43ClN6O8

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Phomopsinamine A
目录号:
HY-P10589
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