2. Immunology/Inflammation
  3. Nuclear Factor of activated T Cells (NFAT)
  4. (+)-Syringaresinol

(+)-Syringaresinol  (Synonyms: (+)-丁香树脂酚)

目录号: HY-126030 纯度: 99.50%
COA 产品使用指南

摩尔计算器

(+)-Syringaresinol，一种木脂素，是 NFAT 转录因子抑制剂，IC50 值为 329.4 μM。(+)-Syringaresinol 也可用于淋巴细胞白血病的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(+)-Syringaresinol Chemical Structure

(+)-Syringaresinol Chemical Structure

CAS No. : 21453-69-0

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥3800
In-stock
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of (+)-Syringaresinol:

(+)-Syringaresinol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(+)-Syringaresinol, a lignan, is a NFAT transcription factor inhibitor, with an IC50 of 329.4 μM. (+)-Syringaresinol also can be used for the research of lymphocytic leukemia[1][2].

IC50 & Target

IC50: 329.4 μM (NFAT transcription factor)[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 100 μM
Compound: 42
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
[PMID: 18440233]
A549 ED50
13.92 μg/mL
Compound: (+)-syringaresinol
Cytotoxicity against human A549 cells after 7 days
Cytotoxicity against human A549 cells after 7 days
[PMID: 1453182]
A549 ED50
14.9 μg/mL
Compound: 7
Cytotoxicity against human A549 cells after 7 days
Cytotoxicity against human A549 cells after 7 days
[PMID: 1593281]
B16-BL6 IC50
> 100 μM
Compound: 42
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
[PMID: 18440233]
HeLa IC50
> 100 μM
Compound: 42
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
[PMID: 18440233]
HT-1080 IC50
> 100 μM
Compound: 42
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
[PMID: 18440233]
HT-29 ED50
15.5 μg/mL
Compound: 7
Cytotoxicity against human HT-29 cells after 7 days
Cytotoxicity against human HT-29 cells after 7 days
[PMID: 1593281]
HT-29 ED50
2.27 x 10-1 μg/mL
Compound: (+)-syringaresinol
Cytotoxicity against human HT-29 cells after 7 days
Cytotoxicity against human HT-29 cells after 7 days
[PMID: 1453182]
KB IC50
> 47.8 μM
Compound: 10
Cytotoxicity against human KB cells by sulforhodamine B assay
Cytotoxicity against human KB cells by sulforhodamine B assay
[PMID: 26928423]
Lewis lung carcinoma cell line IC50
> 100 μM
Compound: 42
Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
[PMID: 18440233]
MCF7 ED50
3.69 μg/mL
Compound: 7
Cytotoxicity against human MCF7 cells after 7 days
Cytotoxicity against human MCF7 cells after 7 days
[PMID: 1593281]
MCF7 ED50
30.31 μg/mL
Compound: (+)-syringaresinol
Cytotoxicity against human MCF7 cells after 7 days
Cytotoxicity against human MCF7 cells after 7 days
[PMID: 1453182]
N9 IC50
2.68 μM
Compound: 16
Antineuroinflammatory activity in mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antineuroinflammatory activity in mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
[PMID: 28073678]
PANC-1 IC50
61.1 μM
Compound: 6
Cytotoxicity against human PANC1 cells after 72 hrs by WST8 assay
Cytotoxicity against human PANC1 cells after 72 hrs by WST8 assay
[PMID: 28495081]
RAW264.7 IC50
> 50 μM
Compound: 6
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay
[PMID: 25592708]
RAW264.7 IC50
> 50 μM
Compound: 18
Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay
Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay
[PMID: 33939429]
RAW264.7 IC50
0.047 mM
Compound: 8
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs
[PMID: 18986199]
RAW264.7 IC50
14.8 μM
Compound: 15
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells preincubated with compound for 1 hr before exposure to LPS measured after 24 hrs by Griess reaction method
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells preincubated with compound for 1 hr before exposure to LPS measured after 24 hrs by Griess reaction method
[PMID: 21435874]
RAW264.7 IC50
21.6 μM
Compound: 15
Antiinflammatory activity in mouse RAW264.7 cells assessed as decrease in LPS-induced NO production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as decrease in LPS-induced NO production after 24 hrs by Griess assay
[PMID: 25666824]
Vero IC50
> 47.8 μM
Compound: 10
Cytotoxicity against African green monkey Vero cells by sulforhodamine B assay
Cytotoxicity against African green monkey Vero cells by sulforhodamine B assay
[PMID: 26928423]
体外研究
(In Vitro)

(+)-Syringaresinol inhibits the growth of P-388 cells, with an ED50 0.41 μg/mL[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(+)-Syringaresinol 相关抗体:
分子量

418.44

Formula

C22H26O8
CAS 号
性状

固体

颜色

White to off-white

中文名称

(+)-丁香树脂酚
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

纯度 & 产品资料
参考文献

(+)-Syringaresinol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(+)-Syringaresinol21453-69-0(+)-丁香树脂酚Nuclear Factor of activated T Cells (NFAT)lignanNFATtranscriptionfactorlymphocyticleukemiaInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
(+)-Syringaresinol
目录号：
HY-126030
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z