2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Pomalidomide-amido-C3-piperazine-N-Boc

Pomalidomide-amido-C3-piperazine-N-Boc 

目录号: HY-131186
产品使用指南

摩尔计算器

Pomalidomide-amido-C3-piperazine-N-Boc 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Pomalidomide 的 cereblon 配体和 linker。可用于合成 PROTAC PD-1/PD-L1 degrader-1 (HY-131183)。

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Pomalidomide-amido-C3-piperazine-N-Boc Chemical Structure

Pomalidomide-amido-C3-piperazine-N-Boc Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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100 mg   询价  
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Pomalidomide-amido-C3-piperazine-N-Boc 相关抗体

Top Publications Citing Use of Products

查看 E3 Ligase Ligand-Linker Conjugates 亚型特异性产品:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pomalidomide-amido-C3-piperazine-N-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].

IC50 & Target

Cereblon

 

分子量

555.58

Formula

C27H33N5O8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pomalidomide-amido-C3-piperazine-N-Boc 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pomalidomide-amido-C3-piperazine-N-BocE3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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Pomalidomide-amido-C3-piperazine-N-Boc
目录号：
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