2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. PPARγ agonist 12

PPARγ agonist 12 (compound 9i) 是一种有效的 PPARγ 选择性激动剂，对 PPARγ 和 PPARδ 的 EC50 分别为 3.98 和 15.42 μM。PPARγ agonist 12 改善胰岛素分泌，具有抗糖尿病作用。

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PPARγ agonist 12 Chemical Structure

PPARγ agonist 12 Chemical Structure

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PPARγ agonist 12 相关抗体

Top Publications Citing Use of Products

查看 PPAR 亚型特异性产品:

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PPARα PPARβ/δ PPARγ PPAR PPARδ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PPARγ agonist 12 (compound 9i) is a potent and selective PPARγ agonist with EC50s of 3.98 and 15.42 μM against PPARγ and PPARδ, respectively. PPARγ agonist 12 improves insulin secretion and has anti-diabetic effect[1].

体内研究
(In Vivo)

PPARγ agonist 12 (36 mg/kg，口服；1 次) 对 NA- Streptozotocin (HY-13753) 糖尿病大鼠具有抗糖尿病作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

525.60

Formula

C25H23N3O6S2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PPARγ agonist 12 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PPARγ agonist 12PPARγ agonist12PPARγ agonist-12PPARPeroxisome proliferator-activated receptorsbenzenesulfonamidepancreatichepaticrenal histopathological alterationsInhibitorinhibitorinhibit

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目录号：
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