2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. PPARγ agonist 14

PPARγ agonist 14 (compound 3) 是一种 PPARy 激动剂 (EC50=2.4 μM)，具有抗糖尿病活性。PPARγ agonist 14 能改善细胞内葡萄糖摄入，促进胰岛素释放，降低血糖。此外，PPARγ agonist 14 还通过参与改善线粒体功能，减轻氧化应激和抑制炎症因子的途径。PPARγ agonist 14 可用于神经退行性疾病、神经炎症性疾病等疾病的研究。

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PPARγ agonist 14 Chemical Structure

PPARγ agonist 14 Chemical Structure

CAS No. : 6951-57-1

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1 mg ￥4200
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PPARγ agonist 14 相关抗体

Top Publications Citing Use of Products

查看 PPAR 亚型特异性产品:

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PPARα PPARβ/δ PPARγ PPAR PPARδ

  • 生物活性

  • 纯度 & 产品资料

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生物活性

PPARγ agonist 14 (compound 3) is a PPARy agonist (EC50=2.4 μM) with anti-diabetic activity. PPARγ agonist 14 can improve intracellular glucose uptake, promote insulin release, and lower blood sugar. In addition, PPARγ agonist 14 also improves mitochondrial function, reduces oxidative stress, and inhibits inflammatory factors. PPARγ agonist 14 can be used in the study of neurodegenerative diseases, neuroinflammatory diseases, and other diseases[1].

IC50 & Target[1]

PPARγ

2.4 μM (EC50)

分子量

316.31

Formula

C17H16O6
CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

PPARγ agonist 14 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PPARγ agonist 146951-57-1PPARγ agonist14PPARγ agonist-14PPARPeroxisome proliferator-activated receptorsAgonistshypoglycemicoxidative stressinflammatory factorsneurodegenerative diseasesInhibitorinhibitorinhibit

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