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  4. PQR514

PQR514是一种强效的PI3K抑制剂，具有抗癌活性。PQR514能够抑制癌细胞增殖。PQR514在OVCAR-3异种移植模型中显示出显著的抗肿瘤活性，其所需浓度约为PQR309的八分之一。PQR514具有良好的药代动力学特性，并且对大脑的穿透性很小，使其成为抑制系统性肿瘤的优化候选化合物。

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PQR514 Chemical Structure

PQR514 Chemical Structure

CAS No. : 1927857-55-3

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PQR514 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PQR514 is a potent PI3K inhibitor with anticancer activity. PQR514 is able to inhibit cancer cell proliferation. PQR514 showed significant antitumor activity in the OVCAR-3 xenograft model, with the required concentration being approximately one-eighth that of PQR309. PQR514 has good pharmacokinetic properties and minimal brain penetration, making it an optimized candidate compound for inhibiting systemic tumors[1].

分子量

394.38

Formula

C16H20F2N8O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PQR514 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PQR5141927857-55-3PQR 514PQR-514OthersInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-167876
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