2. PROTAC Protein Tyrosine Kinase/RTK
  3. PROTACs Btk
  4. PROTAC BTK Degrader-2

PROTAC BTK Degrader-2 是一种有效的 BTK PROTAC 降解剂。PROTAC BTK Degrader-2 可有效降低 BTK 蛋白水平。

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PROTAC BTK Degrader-2 Chemical Structure

PROTAC BTK Degrader-2 Chemical Structure

CAS No. : 2250382-66-0

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规格 是否有货
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PROTAC BTK Degrader-2 相关抗体

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PROTAC BTK Degrader-2 is a potent BTK PROTAC degrader. PROTAC BTK Degrader-2 effectively reduces BTK protein levels[1].

体外研究
(In Vitro)

PROTAC BTK Degrader-2 (compound 10; 1 µM; 24 h; Ramos 细胞) 促进培养细胞中的 BTK 降解[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PROTAC BTK Degrader-2 相关抗体:
体内研究
(In Vivo)

PROTAC BTK Degrader-2 (compound 10; 0-175 mg/kg; s.c.) 在大鼠体内选择性降解 BTK[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: male Wistar Han rats[1]
Dosage: 0, 0.35, 35, and 175 mg/kg
Administration: subcutaneous injection
Result: Degraded BTK in a dose-dependent and tissue-biased manner.
分子量

976.97

Formula

C47H54F2N8O13
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PROTAC BTK Degrader-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC BTK Degrader-22250382-66-0PROTAC BTK Degrader2PROTAC BTK Degrader 2PROTACsBtkBruton tyrosine kinaseBTK proteinRamos cellsInhibitorinhibitorinhibit

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目录号：
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