2. PROTAC Immunology/Inflammation
  3. PROTACs STING
  4. PROTAC STING Degrader-2

PROTAC STING Degrader-2 是一种针对 Stimulator of interferon genes (STING) 的蛋白质降解剂 (DC50=0.53 μM)。PROTAC STING Degrader-2 通过共价结合的方式，与 STING 蛋白和 E3 泛素连接酶同时结合，诱导 STING 蛋白的降解。PROTAC STING Degrader-2 可以用于研究 STING 在自身炎症和自身免疫性疾病中的作用 (PINK: STING binder (HY-145009); Blue: VHL ligand (HY-164043); Black: linker)。

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PROTAC STING Degrader-2 Chemical Structure

PROTAC STING Degrader-2 Chemical Structure

CAS No. : 3023095-61-3

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PROTAC STING Degrader-2 相关抗体

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PROTAC STING degrader-2 is a protein Degrader that targets Stimulator of interferon genes (STING) (DC50=0.53 μM). PROTAC STING Degrader-2 is combined with STING protein and E3 ubiquitin ligase in a covalent manner to induce the degradation of STING protein. PROTAC STING Degrader-2 can be used to investigate the role of STING in autoinflammation and autoimmune diseases (PINK: STING binder (HY-145009); Blue: VHL ligand (HY-164043); Black: linker)[1][2].

分子量

1463.67

Formula

C74H79FN10O15S3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PROTAC STING Degrader-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC STING Degrader-23023095-61-3PROTAC STING Degrader2PROTAC STING Degrader 2PROTACsSTINGStimulator of Interferon GenesTMEM173MITAERISMPYSDegraderscovalent bindingautoinflammationautoimmune diseasesInhibitorinhibitorinhibit

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目录号：
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