2. GPCR/G Protein Neuronal Signaling
  3. Cannabinoid Receptor
  4. PSB-KK1445

PSB-KK1445 是一种强效且选择性的 GPR18 激动剂，对人和小鼠的 GPR18 的 EC50 分别为 45.4 nM 和 124 nM。PSB-KK1445 对两种 CB 受体亚型 GPR55 和 GPR183 的选择性均高出 200 倍以上。

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PSB-KK1445 Chemical Structure

PSB-KK1445 Chemical Structure

CAS No. : 885896-54-8

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PSB-KK1445 相关抗体

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CB1 CB2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PSB-KK1445 is a potent and selective GPR18 agonist with EC50s of 45.4 nM and 124 nM for human and mouse GPR18, respectively. PSB-KK1445 displays >200-fold selectivity versus both CB receptor subtypes, GPR55, and GPR183[1].

IC50 & Target

EC50: 45.4 nM (Human GPR18) and 124 nM (Mouse GPR18)[1]
分子量

446.48

Formula

C24H23FN6O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PSB-KK1445 相关分类

  • 摩尔计算器

  • 稀释计算器

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PSB-KK1445885896-54-8Cannabinoid ReceptorselectiveGPR18 agonistInhibitorinhibitorinhibit

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产品名称：
PSB-KK1445
目录号：
HY-162618
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