2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 疾病相关化合物库
  6. 抗前列腺癌化合物库
抗前列腺癌化合物库 - Anti-Prostate Cancer Compound Library

Cat. No.: HY-L124

癌症是世界人口死亡的主要原因之一，其中前列腺癌是男性中最常见的恶性肿瘤之一。多种分子机制参与前列腺癌的发生发展，包括前列腺癌常见存活因子(IGF-1)、生长因子(TGF-α，EGF) 、Wnt、Hedgehog、NF-κB以及mTOR等信号通路。这为前列腺癌的治疗提供了潜在的治疗靶点。

MCE精心收录了 2,400 化合物，具有明确或潜在的抗前列腺癌活性。MCE抗前列腺癌化合物库是抗前列腺癌药物筛选及相关研究的有用工具。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 抗前列腺癌化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，2,340 个产品以 10 mM 浓度提供，55 个产品以 2 mM 浓度提供，5 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 2,400 compounds for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of anti-prostate cancer drugs.

•   Target diverse, medicinally active and cell permeable.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

产品详情

Product Details

Formulation:

A collection of 2,400 anti-prostate cancer inhibitors supplied as pre-dissolved Solutions or Solid
Solution: 2,340 compounds supplied in 10 mM solution, 55 compounds supplied in 2 mM solution, 5 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice

化合物库组成

Composition

NF-κB (245)

EGFR (197)

PI3K (187)

COX (150)

JAK (123)

Akt (115)

mTOR (96)

FGFR (82)

STAT (77)

ERK (76)

Src (76)

VEGFR (72)

Wnt (60)

HSP (44)

PDGFR (43)

IKK (42)

FLT3 (36)

CDK (35)

PARP (27)

HIV (26)

c-Kit (25)

c-Myc (23)

PPAR (22)

IAP (21)

JNK (18)

PKA (18)

AMPK (17)

MMP (17)

Raf (17)

MEK (15)

HDAC (14)

FAK (13)

PKC (13)

HSV (12)

PDK-1 (11)

Btk (10)

mAChR (10)

RET (10)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Anti-Prostate Cancer Compound Library
    目录号：
    HY-L124
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