2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. (E,E)-RAMB4

(E,E)-RAMB4 是一种有效的，选择性，强效蛋白酪氨酸磷酸酶-1B (PTP1B) 抑制剂，详细信息请参考专利文献 CN103626692A 中的实施例 1。

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(E,E)-RAMB4 Chemical Structure

(E,E)-RAMB4 Chemical Structure

CAS No. : 919091-61-5

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规格 是否有货
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(E,E)-RAMB4 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(E,E)-RAMB4 is a potent and selective potent protein tyrosine phosphatase-1B (PTP1B) inhibitor extracted from patent CN103626692A, example 1[1].

IC50 & Target

PTP1B[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
B16 IC50
4.1 μM
Compound: 4b
Cytotoxicity against Mus musculus (mouse) B16 cells assessed as growth inhibition after 72 hr by MTT assay
Cytotoxicity against Mus musculus (mouse) B16 cells assessed as growth inhibition after 72 hr by MTT assay
10.1007/s00044-013-0557-9
L1210 IC50
3.6 μM
Compound: 4b
Cytotoxicity against Mus musculus (mouse) L1210 cells assessed as growth inhibition after 72 hr by MTT assay
Cytotoxicity against Mus musculus (mouse) L1210 cells assessed as growth inhibition after 72 hr by MTT assay
10.1007/s00044-013-0557-9
分子量

413.12

Formula

C19H13Cl4NO
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(E,E)-RAMB4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(E,E)-RAMB4919091-61-5PhosphataseInhibitorinhibitorinhibit

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